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Elevated levels of NLRP3 are associated with PD once removing those with self reported NSAID use.
| Controls | PD | P univariate | Odds ratioa | (95% CI) | Pa | |
|---|---|---|---|---|---|---|
| N = 119 | N = 71 | |||||
| Age (mean (SD)) | 69.95 (9.90) | 68.42 (7.50) | 0.26 | |||
| Sex = Male (%) | 53 (44.5) | 42 (59.2) | 0.072 | |||
| NSAID = Yes (%) | None | None | ||||
| NLRP3 16.2+ ng/mL (%)—90th percentile | 12 (10.1) | 16 (22.5) | 0.033 | 2.46 | (1.08−5.76) | 0.033 |
aMultivariable logistic regression model including age, sex (P = 0.033).
