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. 2020 Nov 27;124(1):228–236. doi: 10.1038/s41416-020-01162-3

Fig. 5. NCB-0846 inhibits metastatic potential.

Fig. 5

a Representative images of lungs (from top to bottom: unfixed, formalin-fixed, and HE-stained tissue sections) resected from mice 7 weeks after injection of A549 cells treated with TGF-β1 (5 ng/mL) and DMSO, TGF-β1 and NCB-0846 (3 µM) or TGF-β1 and NCB-0970 (3 µM) for 48 h. Scale bar represents 5 mm. b Summed areas of metastases relative to the total lung areas of mice injected with A549 cells treated as described in the legend to Fig. 5a. Error bars represent SD. ***P < 0.001. c Wet lung weights of mice injected with A549 cells treated as described in the legend to Fig. 5a. Error bars represent SD. ***P < 0.001; **P < 0.01.