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. 2020 Dec 31;13:1219–1243. doi: 10.2147/JIR.S286199

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© 2020 Balkrishna et al.

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Cytological examination of the kidney after staining with Hematoxylin and Eosin at 200X magnification. (A) Normal Control (B). Humanized zebrafish with xenotransplanted A549 cells (HZF) (C). Diseased fish with SARS-CoV-2 spike protein (HZF-SARS-CoV-2-S) (D). Dexamethasone (0.08 µg/kg) treatment (E). Divya-Swasari-Vati treatment (6 µg/kg) (F). Divya-Swasari-Vati treatment (28 µg/kg) (G). Divya-Swasari-Vati treatment (142 µg/kg). Black arrowheads depict the nuclei of normal cells, yellow represent degenerative cells, while the red arrowheads depict necrotic cells.