Table 4.
Quantification of the Immune Cell Infiltration in the Air Bladder Cytology. Infiltration of Lymphocytes, Macrophages, and Granulocytes Was Quantified on a Hematoxylin and Eosin Stained Air Bladder from Each Fish. The Results are Expressed as Mean±SD. Statistical Analysis Was Performed Using ANOVA and Significance as Denoted by * P<0.0001 When Compared with the HFZ-CoV2-S Group
| Study Groups | 4 Day | 7 Day | ||||
|---|---|---|---|---|---|---|
| Granulocyte | Macrophage | Lymphocyte | Granulocyte | Macrophage | Lymphocyte | |
| Control | 0 | 0 | 0 | 0 | 0 | 0 |
| HZF | 0 | 0 | 0 | 0 | 0 | 0 |
| HZF-CoV-2-S | 11±5.2 | 7±3.5 | 0 | 0 | 0 | 0 |
| Dexamethasone | 5*±2.9 | 0* | 20*±5.0 | 0 | 9*±5.4 | 10*±6.2 |
| DSV-6 µg/kg | 7.08*±4.6 | 0* | 31*±6.6 | 0 | 0 | 23.71*±5.0 |
| DSV-28 µg/kg | 5.33*±3.1 | 0* | 53.96*±5.7 | 0 | 0 | 19.17*±6.8 |
| DSV-142 µg/kg | 3.42*±3 | 0* | 113.29*±5.5 | 0 | 0 | 16*±6.3 |