Figure 2.

Dystrophin mRNA expression in human tissues. Shown is RNAseq data from multiple human tissues from the genome browser (genome.ucsc.edu). Dystrophin is highly expressed in all types of muscle (skeletal muscle, cardiac muscle, visceral smooth muscle, vascular smooth muscle), peripheral nerve, and some neurons. Dystrophin deficiency leads to pathology in most or all these tissues, but depending on the relative position of the gene promoter relative to the mutation involved.