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. 2020 Dec 22;11:615308. doi: 10.3389/fgene.2020.615308

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Copyright © 2020 Bai, Liu, Guo, Lin, Song, Jin, Liu, Guo, Liang, Song, Wang, Qu, Guo, Jiang, Liu and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Using | logfc | > 1.0 and adj p < 0.05 as cut-off criteria, the differentially expressed genes in TCGA and GSE45114 data sets of Hepatocellular carcinoma (HCC) were identified. (A) Volcano maps of differentially expressed genes in the TCGA dataset. (B) Volcano map of differentially expressed genes in the GSE45114 dataset. (C) Heatmap of 100 differentially expressed genes in the TCGA dataset. (D) Heatmap of 100 differential genes in the GSE45114 dataset. (E) Venn diagram of gene crossover between differential expression gene list and co-expression module. A total of 37 overlapping genes were located at the intersection of the differential expression gene list and the co-expression module.