Table 1.
Estimates of the incidence (per 1000 children per year) and number of human metapneumovirus-associated acute lower respiratory infection cases in children younger than 5 years in the community in 2018, by age group, and by World Bank income level and level of child mortality by setting (low vs high)
| LMICs | UMICs | HICs | Settings with low child mortality | Settings with high child mortality | |
|---|---|---|---|---|---|
| 0–5 months | |||||
| Studies, n | 5 | 1 | 0 | 0 | 6 |
| Incidence (per 1000 children per year)* | 30·2 (7·8–109·8) | NA | NA | NA | 35·4 (12·0–99·3) |
| Episodes (thousands) | 1337 (359–4983) | NA | NA | NA | 1629 (570–4662) |
| 6–11 months | |||||
| Studies, n | 5 | 1 | 0 | 0 | 6 |
| Incidence (per 1000 children per year)* | 30·7 (12·2–75·1) | NA | NA | NA | 32·8 (16·0–65·9) |
| Episodes (thousands) | 1347 (546–3327) | NA | NA | NA | 1496 (740–3026) |
| 12–59 months | |||||
| Studies, n | 4 | 1 | 0 | 0 | 5 |
| Incidence (per 1000 children per year)* | 23·1 (16·7–31·9) | NA | NA | NA | 21·0 (15·4–28·6) |
| Episodes (thousands) | 7923 (5743–10 933) | NA | NA | NA | 7490 (5506–10 192) |
| 0–59 months† | |||||
| Studies, n‡ | 5 (1) | 2 (1) | 3 (2) | 4 (3) | 6 (1) |
| Incidence (per 1000 children per year)* | 21·3 (15·5–29·3) | 16·5 (8·3–32·8) | 22·6 (13·4–38·2) | 18·9 (11·2–31·9) | 22·1 (17·0–28·7) |
| Episodes (thousands) | 9202 (6711–12 620) | 3019 (1521–5996) | 1436 (854–2415) | 4347 (2588–7304)§ | 9891 (7620–12 842)§ |
Data in parentheses are estimated uncertainty ranges. Data were imputed using a multiple imputation approach. Meta-analyses were only done when two or more studies were available. Settings in which the under-5 mortality rate was higher than the median under-5 mortality rate for 2018, were considered high child mortality settings, and settings in which the under-5 mortality rate was lower than the median under-5 mortality rate for 2018, were considered low child mortality settings. LMICs=lower-middle income countries. UMICs=upper middle-income countries. HICs= high-income countries. NA=not available.
Derived from meta-analysis.
Estimates were calculated by applying rates for children aged 0–59 months to the population estimates.
Data in parentheses are the number of imputed studies.
Global number of human metapneumovirus-associated acute lower respiratory infections cases in children aged 0–59 months was 14·2 million (uncertainty range 10·2 million to 20·1 million), which was calculated by adding estimates from the two child mortality setting groups.