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. Author manuscript; available in PMC: 2021 Oct 15.
Published in final edited form as: Toxicol Lett. 2020 Aug 21;333:290–302. doi: 10.1016/j.toxlet.2020.08.007

Figure 3.

Figure 3

Role of necrosis regulated by RIPK3 in triptolide-induced hepatotoxicity. (A) Expression of Ripk3 and Mlkl gene in control and mice treated with 0.8 mg/kg of triptolide. (B) Serum ALT and AST levels from control and 0.8 mg/kg triptolide-treated mice. (C) Micrographs of H&E stained liver sections (200×). Black arrows indicated apoptosis and black arrowheads indicated necrosis. The data were expressed as mean ± SEM (n=8). Statistical analyses were performed with Student’s t tests. *p <0.05, **p<0.01.