Table 2. Hazard Ratios (95% CI) for Substance Use Disorder in the Study Cohort With and Without ASDa.
| Outcome | With ASD (n = 6599) | Without ASD (n = 26 396) | Hazard ratio (95% CI) | ||||
|---|---|---|---|---|---|---|---|
| Persons at risk, No. | Event, No. | Crude incidence per 100 000 person-years | Persons at risk, No. | Event, No. | Crude incidence per 100 000 person-years | ||
| Substance use disorder | 6599 | 128 | 723 | 26 396 | 410 | 350 | 2.33 (1.89-2.87) |
| Alcohol use disorder | 6599 | 84 | 474 | 26 396 | 299 | 256 | 2.07 (1.60-2.63) |
| Drug use disorder | 6599 | 44 | 248 | 26 396 | 111 | 95 | 3.00 (2.15-4.58) |
Abbreviations: ASD, autism spectrum disorder; CCI, Charlson Comorbidity Index.
a
Adjusted for behavioral psychotherapy, sex, age, years of education, marital status, psychiatric comorbidities, CCI score, season of diagnosis, levels of care, frequency of psychiatric and nonpsychiatric hospitalizations, length of admission, urbanicity of residence, monthly income, and follow-up period.