Table 3. Pooled and Stratified Results for the Effect of Maternal Oxygen Supplementation vs Room Air on Neonatal Outcomes.
| Characteristic | No. of studies | No. of patients | Measure of effect | Effect size (95% CI) | I2 value | P value | |
|---|---|---|---|---|---|---|---|
| Oxygen | Room air | ||||||
| All studies | |||||||
| 1-min Apgar score | 8 | 526 | 456 | WMD | −0.13 (−0.30 to 0.04) | 71.68 | .001 |
| 5-min Apgar score | 8 | 526 | 456 | WMD | −0.12 (−0.27 to 0.04) | 99.91 | <.001 |
| NICU admission | 4 | 333 | 340 | RR | 0.87 (0.44-1.73) | 0.00 | .64 |
| Scheduled CD | |||||||
| 1-min Apgar score | 6 | 439 | 366 | WMD | −0.20 (−0.40 to −0.01) | 62.60 | .02 |
| 5-min Apgar score | 6 | 439 | 366 | WMD | −0.16 (−0.36 to 0.04) | 99.30 | <.001 |
| NICU admission | 1 | 30 | 30 | RR | 1.00 (0.02-48.82) | NA | NA |
| Labor | |||||||
| 1-min Apgar score | 2 | 87 | 90 | WMD | 0.08 (−0.02 to 0.19) | 0.00 | .32 |
| 5-min Apgar score | 2 | 87 | 90 | WMD | −0.12 (−0.27 to 0.04) | 0.01 | >.99 |
| NICU admission | 3 | 303 | 310 | RR | 0.87 (0.44-1.73) | 0.00 | .43 |
Abbreviations: CD, cesarean delivery; NA, not applicable; NICU, neonatal intensive care unit; RR, relative risk; WMD, weighted mean difference.