Table 1. Main Demographic and Clinical Characteristics of Participants in the Study.
| Characteristic | Mean (SD) [range] | P value | |
|---|---|---|---|
| Healthy control individuals | Patients with MS | ||
| Total No. | 196 | 1212 | NA |
| Age, y | 40.4 (8.6) [20.2-60.9] | 41.1 (11.1) [18.0-77.2] | .38 |
| Female sex, No. (%) | 130 (66.3) | 784 (64.7) | .87 |
| Male sex, No. (%) | 66 (33.7) | 428 (35.3) | .87 |
| EDSS score, median (range) | NA | 2.0 (0.0-8.5) | NA |
| Disease duration, y | NA | 10.5 (9.0) [0.20-55.2] | NA |
| Age at onset, y | NA | 29.8 (9.9) [7.0-68.9] | NA |
| Education, y | 12.5 (3.4) [5.0-19.0] | 12.2 (3.8) [5.0-24.0] | .38 |
| FSS score | NA | 14.9 (17.4) [1.0-63.0] | NA |
| MADRS score | NA | 10.1 (9.3) [0.0-59.0] | NA |
Abbreviations: EDSS, Expanded Disability Status Scale; FSS, Fatigue Severity Scale; MADRS, Montgomery-Åsberg Depression Rating Scale; MS, multiple sclerosis; NA, not applicable.