Table 1.

Patient characteristics.

N	M/F	Age	Type	FISH:S/H	N.Previous lines	Dara-therapy	N.Dara previous infusions	IRR1 dose	N.Rapid infusions	IRR in Rapid infusions	Disease status before Dara	Bestresponse	PD:Y/N	FUO/infection	A/D
1	M	68	IgA κ	S	3	DVd	16	No	4	None	RR	PR	Y	Yes	Dead
2	M	84	IgG κ	S	6	DRd	3	No	28	None	RR	PR	N	Yes	Alive
3	M	57	IgG κ	ND	4	DVd	5	No	18	None	RR	PR	N	Yes	Alive
4	M	60	BJ.κ	H	6	DRd	3	No	24	None	RR	PR	Y	Yes	Dead
5	M	53	IgG κ	H	2	DPd	2	Yes	12	None	RR	SD	Y	Yes	Dead
6	M	71	IgG κ	N	1	DRd	2	No	21	None	RR	CR	N	No	Alive
7	M	58	BJ.λ	S	1	DRd	2	Yes	19	None	RR	PR	N	Yes	Alive
8	F	62	IgG λ	N	6	Dara alone	13	No	1	None	RR	PR	Y	Yes	Dead
9	M	57	IgG λ	N	3	DRd	5	Yes	7	None	RR	SD	Y	No	Dead
10	M	65	IgG λ	N	1	DRd	2	Yes	4	None	RR	VGPR	N	Yes	Alive
11	M	63	BJ λ	N	1	Dara alone	2	No	19	None	RR	VGPR	N	Yes	Alive
12	M	63	IgG λ	ND	1	Dara alone	12	No	18	None	RR	PR	N	No	Alive
13	M	49	IgG/k	H	6	Dara Alone	13	No	4	None	RR	PR	Y	No	Dead
14	F	55	IgG/k	H	2	DVd	2	No	11	None	RR	PR	N	No	Alive
15	F	63	IgG/k	S	6	DRd	2	No	9	None	RR	VGPR	N	No	Alive
16	M	64	BJ/λ	S	2	DRd	2	No	7	None	RR	VGPR	N	No	Alive
17	M	45	IgG/k	S	1	DRd	2	No	1	None	RR	NA	N	No	Alive
18	M	61	IgG/k	S	4	DVd	2	No	1	None	RR	NA	N	No	Alive
19	F	63	BJ/λ	S	1	DRd	2	Yes	1	None	RR	NA	N	No	Alive
20	F	51	IgG κ	S	1	DART4MM	2	No	21	None	CR-MRD pos	CR	N	No	Alive
21	F	63	IgG κ	S	1	DART4MM	2	No	14	None	CR-MRD pos	CR	N	No	Alive
22	M	71	IgA λ	S	1	DART4MM	2	No	14	None	VGPR	sCR-MRD neg	N	No	Alive
23	M	62	IgG k	S	1	DART4MM	2	No	16	None	CR-MRD pos	CR	N	No	Alive
24	F	65	IgG k	S	1	DART4MM	2	No	16	None	VGPR	VGPR	N	No	Alive
25	F	72	IgG λ	H	1	DART4MM	3	Yes	26	None	VGPR	VGPR	Y	No	Alive
26	F	78	IgG κ	N	1	DART4MM	2	Yes	30	None	VGPR	CR	N	No	Alive
27	M	71	IgG κ	S	1	DART4MM	2	No	14	None	VGPR	sCR-MRD neg	N	No	Alive
28	M	66	IgG λ	ND	1	DART4MM	2	No	14	None	VGPR	CR-MRD neg	N	No	Alive
29	F	65	IgG λ	S	1	DART4MM	2	Yes	14	None	CR-MRD pos	CR-MRD neg	N	No	Alive
30	M	55	BJ λ	ND	1	DART4MM	2	No	14	None	CR-MRD pos	CR-MRD neg	N	No	Alive
31	M	58	IgG κ	S	1	DART4MM	2	Yes	14	None	VGPR	CR-MRD neg	N	No	Alive
32	M	48	IgG λ	S	1	DART4MM	2	No	14	None	CR-MRD pos	CR-MRD neg	N	No	Alive
33	M	70	IgG/k	S	1	DART4MM	2	No	18	None	VGPR	VGPR	N	No	Alive
34	F	66	IgG/k	S	1	DART4MM	2	No	12	None	VGPR	CR	N	No	Alive
35	M	65	IgG/k	S	1	DART4MM	2	Yes	15	None	VGPR	VGPR	N	No	Alive
36	M	66	IgG k	S	1	DART4MM	2	No	5	None	VGPR	NA	N	No	Alive
37	M	62	IgG/k	S	1	DART4MM	2	Yes	2	None	CR-MRD pos	NA	N	No	Alive
38	M	52	IgG/k	S	1	DART4MM	2	Yes	1	None	VGPR	NA	N	No	Alive
39	F	59	IgG/k	S	1	DART4MM	2	Yes	1	None	VGPR	NA	N	No	Alive

FISH : ND, not done; H = high risk (t 4;14-t14;16-del 17p); S, standard risk (all other anomalies); N, normal; DVd, dara, velcade, dexamethasone; DRd, Dara, Revlimid, dexamethasone; DPd, Dara, Pomalidomide, dexamethasone; NA, not applicable (too early for assessment); IRR, infusion-related reaction; FUO, fever of unknown origin.

N Rapid infusions and IRRR in Rapid infusions columns are evidenced in bold.