Fig. 1.

SCH58261 enhances neural cell survival post-injury. The SHAM group received no treatment, the INJ group was exposed to 20 min of oxygen-glucose deprivation (OGD), and the INJ+SCH58261 group was exposed to 20 min of OGD and received 1 μM SCH58261. (A) Immunofluorescent images of dead (red areas) and living (green areas) cells. (B) Quantification of neural cell survival. (C) Immunofluorescent images of pyknotic nuclei (refer to the white arrows pointing to the dense, brighter nuclei). (D) Quantification of apoptosis. Scale bar: 20 µm. Data are shown as mean ± SEM (n = 6 per group). (*) indicates p < 0.05, (**) indicates p < 0.01, and (***) indicates p < 0.001.