Fig. 2.

SCH58261 protects against loss of MBP⁺ OLs post-injury. The SHAM group received no treatment, the INJ group was exposed to 20 min of OGD, and the INJ+SCH58261 group was exposed to 20 min of OGD and received 1 μM SCH58261. (A) Immunofluorescent images of MBP⁺ OLs (red areas) and pyknotic nuclei (refer to the white arrows pointing to the dense, brighter green nuclei). (B) Quantification of viable MBP⁺ OLs. (C) Quantification of apoptotic MBP⁺ OLs. Scale bar: 10 µm. Data are shown as mean ± SEM (n = 6 per group). (**) indicates p < 0.01 and (***) indicates p < 0.001.