Fig. 3.

SCH58261 protects against loss of NG2⁺ OPCs post-injury. The SHAM group received no treatment, the INJ group was exposed to 20 min of OGD, and the INJ + SCH58261 group was exposed to 20 min of OGD and received 1 μM SCH58261. (A) Immunofluorescent images of NG2⁺OPCs (red areas) and pyknotic nuclei (refer to the white arrows pointing to the dense, brighter green nuclei). (B) Quantification of viable NG2⁺ OPCs. (C) Quantification of apoptotic NG2⁺ OPCs. Scale bar: 10 µm. Data are shown as mean ± SEM (n = 6 per group). (*) indicates p < 0.05 and (***) indicates p < 0.001.