Fig. 10.

DON-induced DNA damage (Olive tail movement) and its attenuation by pre-treatment with QUE in SH-SY5Y cells. (a) Protective efficacy of QUE (pre-treated for 6 h) against DON induced DNA damage for 24 h. (b) Depict the protective efficacy of QUE pre-treatment (1 mM for 6 h) against DON (100 µM) induced DNA damage. The images were captured at a magnification of 400x. The studies were executed in six replicates (n = 6) and results were expressed as mean ± SD. The statistical difference between control and test groups was determined following Dunnett’s test and significance was determined at p ≤ 0.05 (* ≤ 0.05, ** < 0.01, and *** < 0.001). The p-value was considered as not significant at > 0.05 and denoted as ‘#’.