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DHA inhibited tumor growth in KpB mice. KpB mice were treated with vehicle (control) or DHA (15 mg/kg, daily) for 4 weeks when the tumors reached 0.1 cm in size. DHA significantly inhibited tumor volume and tumor weight (N=15 animals per group) as compared to the vehicle treated controls (A and B). Immunohistochemistry results showed that DHA decreased the expression of Ki-67, phos-S6 and BCL-XL and increased Bip expression in the ovarian tumor tissues (C). *P<0.05; **P<0.01.
