Skip to main content
. 2020 Dec 1;10(12):4498–4512.

Figure 4.

Figure 4

(A) Circulating sPD-L1 protein measurement in 16 healthy subjects and 96 patients with ENKTL collected at diagnosis. (B-G) The sPD-L1 level are significantly higher in patients with elevated LDH level (B), advanced stage disease (C), extranodal sites ≥ 2 (D), IPI ≥ 2 (E), PINK > 1 (F) and CR status (G) in ENKTL. *, P < 0.05; **, P < 0.001, ***, P < 0.0001. (H) No correlation between the exoPD-L1 in patients’ plasma and the soluble PD-L1 level; Spearman’s correlation at P=0.16, r=0.02. (I, J) Kaplan-Meier estimates of PFS (I) and OS (J) considering the cutoff point for sPD-L1 at 219.0 pg/ml.