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. 2020 Nov 11;28(1):948–955. doi: 10.1016/j.sjbs.2020.11.003

Fig. 1.

Fig. 1

Schematic diagram of the treatment procedure. Paternal (F0 generation) exposure to BPA induces testis abnormalities in the F1 generation, implying intergenerational transfer of testis abnormalities. Offspring of F0 (F1 generation) were not exposed directly to BPA. F0 male somatic cells (e.g. testis) and germ cells (e.g. sperms) were directly exposed to BPA. Parental BPA exposure caused abnormalities in the germlines (F1 generation).