BPA exposure reduced quality of sperm parameters of F0 and F1 generation BPA lineage mice. F0 male mice were exposed to the same conditions of sham, vehicle or BPA. Quantifications of (A) sperm counts, (B) sperm motility, and (C) sperm morphology in F0 and F1 generations. Data are expressed as mean ± SEM (n = 6). (*) indicates < 0.05, (**) indicates p < 0.01, and (***) indicates p < 0.001. Data are presented as mean ± SEM for at least 6 independent biological replicates. (*) indicates p < 0.05, (**) indicates p < 0.001, and (***) indicates p < 0.001.