Table 2.

Effect of SMR (300 mg/kg) on serum alanine aminotransferase (ALT), aspartate amino transferase (AST), alkaline phosphatase (ALP) activities in paracetamol induced liver fibrosis in rat.

Groups	AST Median ± SD	ALP Median ± SD	ALT Median ± SD	HCV	GSH Median ± SD	TBARs Median ± SD
Control	59.24 ± 1.89a	206.89 ± 9.761a	45.98 ± 2.35a	Negative	0.535 ± 0.08a	61.358 ± 21.22a
Paracetamol	206.33 ± 11.98b	601 ± 18.25b	122 ± 5.65b	Positive	0.237 ± 0.06b	11.128 ± 56.55b
SMR + Paracetamol	70.44 ± 7.84bc	250 ± 11.97bc	61.33 ± 4.78bc	Negative	0.307 ± 0.10bc	56.55 ± 15.78bc
SMR + paracetamol + HG	77.31 ± 13.5 cd	258 ± 12.76 cd	62.78 ± 2.03 cd	Negative	0.389 ± 0.08 cd	60.061 ± 12.49 cd

Values expressed as mean ± SD (n = 6). Significant difference vs. ^a respective control, ^b respective paracetamol, ^c represented SMR, ^d respective diabetic groups, each at p < 0.05.