Table 3.
Factors associated with post haemodialysis hyperglycaemia (PHH) using simple logistic regression
| PHH |
Test statistic | P Value | Crude Odds ratio (95% CI) | |||
|---|---|---|---|---|---|---|
| Increase | Decrease | |||||
| Diabetes | 3.989 | <0.01 | ||||
| Yes | 74 (72.5) | 17 (37.0) | 4.5 (2.2, 9.6) | |||
| No | 28 (27.5) | 29 (63.0) | Reference | |||
| Gender | 0.650 | 0.515 | ||||
| Female | 48 (47.1) | 19 (41.3) | 1.26 (0.63, 2.58) | |||
| Male | 54 (52.9) | 27 (58.7) | Reference | |||
| Smoking | -0.991 | 0.322 | ||||
| Yes | 8 (7.8) | 6 (13.0) | 0.56 (0.19, 1.82) | |||
| No | 94 (92.2) | 40 (87.0) | Reference | |||
| BMI (kg/m2) | 22.7 | <0.01 | ||||
| Normal (18.5 – 22.9) | 16 (15.7) | 10 (21.7) | Reference | |||
| Underweight (<18.5) | 2 (2.0) | 3 (6.5) | 0.877 | 0.380 | 2.40 (0.34, 20.77) | |
| Overweight (23.0 – 24.9) | 14 (13.7) | 8 (17.4) | 0.951 | 0.342 | 2.63 (0.36, 23.37) | |
| Obese 1 (25.0 – 29.9) | 41 (40.2) | 16 (34.8) | 1.404 | 0.160 | 3.84 (0.59, 31.31) | |
| Obese 2 (>30.0) | 29 (28.4) | 9 (19.6) | 1.592 | 0.111 | 4.83 (0.70, 41.37) | |
| IHD | 1.53 | 0.125 | ||||
| Yes | 30 (29.4) | 8 (17.4) | 1.98 (0.86, 5.01) | |||
| No | 72 (70.6) | 38 (82.6) | Reference | |||
| Gout | -0.600 | 0.549 | ||||
| Yes | 8 (7.8) | 5 (10.9) | 0.70 (0.22, 2.43) | |||
| No | 94 (92.2) | 41 (89.1) | Reference | |||
| Hyperlipidaemia | 0.999 | 0.318 | ||||
| Yes | 60 (58.8) | 23 (50.0) | 1.43 (0.71, 2.89) | |||
| No | 42 (41.2) | 23 (50.0) | Reference | |||
| Stroke | 0.147 | 0.883 | ||||
| Yes | 5 (4.9) | 2 (4.3) | 1.13 (0.23, 8.13) | |||
| No | 97 (95.1) | 44 (95.7) | Reference | |||
| Hypertension | 0.0808 | 0.419 | ||||
| Yes | 100 (98.0) | 44 (95.7) | 2.27 (0.27, 19.43) | |||
| No | 2 (2.0) | 2 (4.3) | Reference | |||
| Mean (SD) | ||||||
| Age (years) | 56.6 (12.0) | 49.2 (10.2) | 3.383 | <0.01 | 1.06 (1.03, 1.10) | |
| Duration HD (years) | 3.9 (3.1) | 4.5 (3.4) | -0.983 | 0.326 | 0.95 (0.86, 1.06) | |
| BMI (kg/m2) | 27.3 (5.1) | 25.6 (5.8) | 1.756 | 0.079 | 1.06 (0.99, 1.14) | |
| HbA1c (%) | 6.9 (1.6) | 6.1 (1.5) | 2.613 | <0.01 | 1.44 (1.12, 1.94) | |
| HSCRP (mg/L) | 8.4 (8.3) | 6.4 (6.1) | 1.42 | 0.155 | 1.04 (0.99, 1.10) | |
| Ferritin (μg/L) | 622.2 (413.1) | 560.2 (421.7) | 0.807 | 0.412 | 1.00 (0.99,1.00) | |
| Albumin (mmol/L) | 38.5 (4.0) | 39.9 (3.0) | -2.109 | 0.035 | 0.89 (0.80, 9.88) | |
| Clearance (%) | 69.5 (9.0) | 69.0 (9.4) | 0.260 | 0.795 | 1.01 (0.97, 1.05) | |
| LDL (mmol/L) | 3.0 (1.2) | 3.0 (1.0) | 0.115 | 0.908 | 1.02 (0.75, 1.39) | |
| HDL (mmol/L) | 0.99 (0.2) | 1.0 (0.3) | -1.174 | 0.240 | 0.44 (0.11, 1.74) | |
| HB (g/dL) | 10.44 (1.7) | 10.40 (1.7) | 0.168 | 0.866 | 1.02 (0.83, 1.25) | |
| TG (mmol/L) | 2.3 (1.8) | 1.9 (1.1) | 1.334 | 0.182 | 1.20 (0.94, 1.61) | |
| Transferrin saturation | 24.0 (10.2) | 25.2 (10.9) | -0.611 | 0.541 | 0.99 (0.96, 1.02) | |
| Calcium (mmol/L) | 2.17 (0.21) | 2.16 (0.24) | 0.336 | 0.737 | 1.31 (0.26, 6.34) | |
| Phosphate (mmol/L) | 1.9 (0.6) | 2.1 (0.7) | -1.408 | 0.160 | 0.68 (0.39,1.16) | |
| ALP (U/L) | 148.6 (108.0) | 175.0 (154.4) | -1.169 | 0.242 | 0.99 (0.99, 1.00) | |
| iPTH (pmol/L) | 78.1 (67.6) | 100.5 (102.4) | -1.465 | 0.162 | 0.99 (0.99,1.00) | |
Table 3 shows simple logistic regression analysis of sociodemographic, clinical co-morbidities and blood parameters among patients in cohort (n=148) with post hemodialysis hyperglycemia (PHH). Diabetes, Body Mass Index (BMI) category, Ischemic Heart Disease (IHD), age, glycated hemoglobin (HbA1c), highly sensitive C-reactive protein (hs-CRP) and albumin were significant at P<0.15 to be included in multiple logistic regression.