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. 2021 Jan 5;57(1):2002272. doi: 10.1183/13993003.02272-2020

TABLE 2.

Drug-resistance profile of the 2217 Mycobacterium tuberculosis isolates included in the database stratified by lineage

Lineage R H MDR-TB Z SLIDs FQs XDR-TB
1 (EAI) 32 (1.5) 31 (1.6) 30 (1.5) 13 (1.0) 0 (0.0) 1 (0.2 0 (0.0)
2 (Beijing/East-Asian non-Beijing) 638 (29.7) 632 (31.9) 630 (32.1) 443 (34.4) 337 (48.4) 257 (44.2) 179 (54.1)
3 (Delhi-CAS) 63 (2.9) 53 (2.7) 53 (2.7) 22 (1.7) 2 (0.3) 10 (1.7) 1 (0.3)
4.1 (Euro-American) 390 (18.1) 347 (17.5) 341 (17.4) 206 (16.0) 71 (10.2) 77 (13.3) 38 (11.5)
4.2 (Euro-American) 199 (9.3) 191 (9.6) 189 (9.6) 122 (9.5) 48 (6.9) 49 (8.4) 25 (7.6)
4.3 (LAM) 183 (8.5) 166 (8.4) 163 (8.3) 95 (7.4) 38 (5.5) 50 (8.6) 19 (5.7)
4.4, 4.5, 4.6 (Euro-American) 77 (3.6) 70 (3.5) 69 (3.5) 48 (3.7) 22 (3.2) 5 (0.9) 1 (0.3)
4.7, 4.8, 4.9 (Euro-American) 555 (25.8) 483 (24.3) 476 (24.3) 333 (25.9) 175 (25.1) 131 (22.5) 67 (20.2)
5 (West-Africa 1) 1 (0.0) 1 (0.1) 1 (0.1) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Unknown 13 (0.6) 10 (0.5) 10 (0.5) 4 (0.3) 4 (0.6) 1 (0.2) 1 (0.3)
Total 2151 (97.0) 1984 (89.5) 1962 (88.5) 1286 (58.0) 697 (31.4) 581 (26.8) 331 (15.4)

Data are presented as n (%). R: rifampicin; H: isoniazid; MDR: multidrug resistant; TB: tuberculosis; Z: pyrazinamide; SLID: second-line injectable drug; FQ: fluoroquinolone; XDR: extensively drug resistant.