TABLE 3.
Cross-border clusters identified using an SNP-based approach
| SNP-based cross-border clusters (≤5 SNPs threshold) | |||
| Cross-border cluster name | Isolates n | Countries involved n | Lineage classification |
| snpCL 1 | 30 | 3 | 4.8 (mainly T) |
| snpCL 2 | 20 | 2 | 4.2.1 (Ural) |
| snpCL 3 | 16 | 4 | 4.6.2 (Euro-American) |
| snpCL 4 | 14 | 2 | 4.8 (mainly T) |
| snpCL 5 | 13 | 2 | 4.2.1 (Ural) |
| snpCL 6 | 13 | 3 | 4.8 (mainly T) |
| snpCL 7 | 12 | 3 | 2.2.1 (Beijing) |
| snpCL 8 | 12 | 4 | 4.2.2 (Euro-American) |
| snpCL 9 | 12 | 2 | 4.8 (mainly T) |
| snpCL 10 | 12 | 2 | 4.1.2.1 (Haarlem) |
| snpCL 11 | 10 | 2 | 4.3.3 (LAM) |
| snpCL 12 | 10 | 5 | 4.2.2 (Euro-American) |
| snpCL 13 | 9 | 6 | 2.2.1 (Beijing) |
| snpCL 14 | 7 | 4 | 2.2.1 (Beijing) |
| snpCL 15 | 7 | 5 | 2.2.1 (Beijing) |
| snpCL 16 | 7 | 2 | 2.2.1 (Beijing) |
| snpCL 17 | 5 | 4 | 4.3.3 (LAM) |
| snpCL 18 | 5 | 2 | 2.2.1 (Beijing) |
| snpCL 19 | 5 | 2 | 4.8 (mainly T) |
| snpCL 20 | 5 | 2 | 4.3.3 (LAM) |
| snpCL 21 | 5 | 2 | 4.2.2.1 (TUR) |
| snpCL 22 | 5 | 2 | 4.1.2.1 (Haarlem) |
| snpCL 23 | 4 | 3 | 4.3.3 (LAM) |
| snpCL 24 | 4 | 3 | 2.2.1 (Beijing) |
| snpCL 25–34# | 3 | 2 to 3 | |
| snpCL 35–56¶ | 2 | 2 | |
A sequential number from 1 to 56 was assigned to each cross-border cluster identified by SNP-based analysis, based on the size of the cluster and starting from the largest one. SNP: single nucleotide polymorphism; snpCL: SNP-based cluster. #: 10 clusters comprising three isolates from three (n=1) and two (n=9) countries, with the lineage distribution comprising 2.2.1 Beijing (n=3), 4.8 mainly T (n=2), 4.7 mainly T (n=1), 4.1.2.1 Haarlem (n=2), 4.2.2 Euro-American (n=1) and 4.1.1.1 X-type (n=1); ¶: 22 clusters comprising two isolates from two countries, with the lineage distribution comprising 2.2.1 Beijing (n=7), 4.8 mainly T (n=3), 4.1.2.1 Haarlem (n=3), 4.2.1 Ural (n=2), 4.3.3 LAM (n=2), 4.3.1 LAM (n=1), 4.1.2 Euro-American (n=1), 4.2.2 Euro-American (n=1), 4.9, H37Rv-like (n=1) and 3 Delhi-CAS (n=1).