Table 1.
Nonhuman primate models in breast development and neoplasia research
| Type of Model | Reported Species | References |
|---|---|---|
| Breast Cancer Studies | ||
| Spontaneous mammary neoplasia | Macaca mulatta | [50, 52–54] |
| Macaca fascicularis | ||
| Papio sp. | ||
| Chlorocebus aethiops | ||
| Chemically-induced mammary neoplasia | Macaca mulatta | [55] |
| Macaca fascicularis | ||
| Chlorocebus aethiops | ||
| Breast Developmental and/or Cancer Risk Studies | ||
| HRT or SERM exposure | Macaca fascicularis | [36, 46–49, 56–59] |
| Dietary exposure | Macaca fascicularis | [33, 34, 48, 49, 60] |
| EDC | Macaca mulatta | [61] |
| Other Applications | ||
| Breast profiling at specific developmental stages to model carcinogenesis | Macaca fascicularis | [28, 33–35, 41] |
| Macaca mulatta | ||
| Ex vivo mammary culture model | Macaca mulatta | [51, 62, 63] |
| Macaca fascicularis | ||
| Papio hamadryas anubis | ||
| Callithrix jacchus | ||
HRT Hormone replacement therapy, SERM Selective estrogen receptor modulator, EDC Endocrine disrupting chemicals