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. 2020 Jun 29;190(1):142–149. doi: 10.1093/aje/kwaa122

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© The Author(s) 2020. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Sensitivity analysis for prior event rate ratio (PERR) (over different values of u) and prior event rate difference (PERD) (over different values of d). In the PERR analysis, values for u range between 0.8 and 1.2; represents the primary analysis without adjustment for violations of the common rate-change assumption on the multiplicative scale, and estimates below the gray horizontal line denote benefit from proton pump inhibitors. In the PERD analysis, values for d range between −5 and 5 events per 1,000 person-years; represents the primary analysis without adjustment for violations of the common rate-change assumption on the additive scale, and estimates below the gray horizontal line denote benefit from proton pump inhibitors. For the PERD analysis, incidence rate differences are expressed as differences in events per 1,000 person-years. A) Estimated incidence rate ratio (IRR) denotes the estimated ; B) estimated incidence rate difference (IRD) denotes the estimated . Data for this illustration is from Table 4 in Othman et al. (5).

Inline graphic — Sensitivity analysis for prior event rate ratio (PERR) (over different values of u) and prior event rate difference (PERD) (over different values of d). In the PERR analysis, values for u range between 0.8 and 1.2; represents the primary analysis without adjustment for violations of the common rate-change assumption on the multiplicative scale, and estimates below the gray horizontal line denote benefit from proton pump inhibitors. In the PERD analysis, values for d range between −5 and 5 events per 1,000 person-years; represents the primary analysis without adjustment for violations of the common rate-change assumption on the additive scale, and estimates below the gray horizontal line denote benefit from proton pump inhibitors. For the PERD analysis, incidence rate differences are expressed as differences in events per 1,000 person-years. A) Estimated incidence rate ratio (IRR) denotes the estimated ; B) estimated incidence rate difference (IRD) denotes the estimated . Data for this illustration is from Table 4 in Othman et al. (5).