Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 19;29:0963689720966265. doi: 10.1177/0963689720966265

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 4. — ICS reduced transfusion-related immune modulation of monocytes. Monocyte intracellular cytokine production and expression of surface activation and adhesion molecules following exposure to standard allogenic blood or autologous ICS. X axis: in vitro “transfusion” conditions, preoperative sample (Pre-Op, open black circles), preoperative sample + ABO-compatible allogeneic blood (Pre-Op + ABO, open purple squares), and preoperative sample + their own cell salvage blood (Pre-Op + ICS, open green diamonds). Y axis: median fluorescent intensity of indicated cytokine or surface marker in gated monocytes (CD14⁺). Analysis of variance indicated by bar and P-value with Tukey’s post-test indicated by *P < 0.05, **P < 0.01, ***P < 0.001.

HLA-DR: human leukocyte antigen DR phenotype; ICS: intraoperative cell salvage; IL: interleukin; MCP-1: monocyte chemoattractant protein-1; MIP-1α: macrophage inflammatory protein-1 alfa; TNF-α: tumor necrosis factor alfa.