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. 2020 Sep 3;30(12):1127–1135. doi: 10.1038/s41422-020-00404-6

Fig. 1. Biochemical characterization and cryo-EM studies of MlaFEDB.

Fig. 1

a Diagram of the Mla system for phospholipids transport. The Mla system proteins are labeled A through F. The inner membrane is composed of phospholipids, while the outer membrane is an asymmetric lipid bilayer with an inner leaflet composed of phospholipids and an outer leaflet of lipopolysaccharide. b ATPase activities of MlaFEDB complex in DDM and nanodisc, and MlaFEQEDB in nanodisc. c Assay of the ATP concentration-dependent ATPase activities of nanodisc-embedded MlaFEDB complex. Each point represents mean ± SD. n = 3 biologically independent samples.