Table 3.

Top 25 ADEs suspected to be caused by remdesivir reported in 439 individuals in WHO database (N = 439)

Sl. No.	ADEs	Frequency (%)
1	Hepatic enzyme increased	141 (32.11)
2	Renal Injury	63 (14.4)
3	Blood creatinine increased	49 (11.2)
4	Medication Error	34 (7.7)
5	Product Use in Unapproved Condition	29 (6.6)
6	Respiratory failure	28 (6.4)
7	Tachy or Bradyarrythmia	26 (5.9)
8	Hypotension	24 (5.5)
9	Rash	22 (5.0)
10	Therapy cessation	22 (5.0)
11	Condition Aggravated/Disease Progression	19 (4.3)
12	Sepsis and Septic Shock	18 (4.1)
13	Cardiac and Cardiorespiratory Arrest	17 (3.9)
14	Nausea/Vomiting	15 (3.4)
15	Glomerular filtration rate decreased	14 (3.2)
16	Renal impairment	14 (3.2)
17	Abnormal Hemogram	13 (3.0)
18	Renal failure	13 (3.0)
19	Death	12 (2.7)
20	Multiorgan Disorder/Organ Failure	11 (2.5)
21	Pyrexia	11 (2.5)
22	Hypoxia	11 (2.5)
23	Dialysis	11 (2.5)
24	Diarrhea	10 (2.3)
25	Acidosis	10 (2.3)