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. 2020 Jul 8;34(12):2175–2196. doi: 10.1038/s41433-020-1065-z

Table 3.

Comparative studies on contact lens efficacy and comfort (GP and soft/scleral/hybrid contact lenses).

Author Study design Contact lens type No. of eyes Follow-up (months) Keratometry (D) BCLCVA (logMAR) Contrast sensitivity Wear-time (hours)/comfort Cons
Gupta et al. [19] Randomised comparative trial Rose K vs. Soper 60 3

Sim K max

Rose K: 56.72 ± 4.54

Soper: 55.5 ± 3.88

Rose K: 0.06 ± 0.09

Soper: 0.09 ± 0.1

NA Rose K group had better comfort scores NA
Levit et al. [24] Randomised controlled trial Zenlens (Scleral lens)a vs. Rose K 34 4 Kmax (mean): 6.2 mm (±0.60) No significant difference (P = 0.563) No significant difference (P = 0.316) SL had higher subjective comfort scores (P = 0.002) NA
Kazanci et al. [20] Comparative Rose K, Boston Equalens II, Boston 7, CFKE 229 ≥12 NA Significant ↑ VA (P < 0.05) NA Rose K: 9.7 ± 0.88; Boston Equalens II: 8.0 ± 1.39; Boston 7: 7.9 ± 1.19; CFKE: 8.7 ± 2.24 NA
Fernandez-Velazquez et al. [22] Retrospective comparative KIC and Rose K 94 KIC, 97 Rose-K ≥6 Sim K steep: 47.90 ± 3.70 (KIC), 49.00 ± 3.42 (Rose K) 0.04 ± 0.07 (KIC), 0.04 ± 0.07 (Rose K) NA 11.6 ± 1.5 (KIC), 11.1 ± 1.5 (Rose K) NA
Betts et al. [23] Case series Rose K and habitual 20 2 Steep K: 51.74 ± 4.48 (steep eye) NA Improvement 0.67 ± 1.28 points (5-point scale)

15.33 ± 2.74 (Rose K)

14.89 ± 2.76 (habitual)

NA
Hassani et al. [25] Comparative GP, ClearKone SynergEyes hybrid 28 NA Mean K: 7.23 ± 0.62 (mm)

ClearKone: 0.022 ± 0.03

GP: 0.057 ± 0.09 (P = 0.004)

NA NA NA
Carracedo et al. [26] Comparative study ClearKone vs. habitual CL 33 1 Mean K steep: 55.11 ± 9.37

0.16 ± 0.12 (habitual)

−0.006 ± 0.058 (ClearKone)

1.26 ± 0.22 (habitual)

1.65 ± 0.19 (ClearKone) (P < 0.001)

VAS comfort score: 8.37 ± 1.43 (ClearKone) NA
Hashemi et al. [27] Comparative case series ClearKone-Synergeyes, GP 40 pts NA

Mean K

ClearKone: 48.68 ± 5.82 (R)

48.99 ± 4.28 (R)

ClearKone: 0.01 ± 0.02 (R)

GP: 0.02 ± 0.03 (R) (P = 0.22)

NA Comfort: ClearKone > GP NA

D diopter, BCLCVA best contact lens corrected visual acuity, K keratometry, max maximum, NA not applicable, VA visual acuity, KIC kerasoft IC, RGP rigid gas permeable, CL contact lens, VAS visual acuity score, R right.

aAlden Opital/Bausch and Lomb, Kingston-upon-Thames, UK.