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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Free Radic Res. 2020 Sep 1;54(7):525–534. doi: 10.1080/10715762.2020.1812597

Figure. 7. Time course of hepatic GSH concentrations (top), Gclc mRNA levels (middle), and Slc3a1 mRNA levels (bottom) after treatment with acetaminophen (300mg/kg, i.p.).

Figure. 7.

GSH was extracted from liver and quantified by UPLC-MS/MS as described in the method. Total liver RNA was isolated and analyzed by the bDNA signal amplification assay for Gclc and Slc3a1 mRNA content. Data are presented as mean ± S.E.M μmol/g tissue or RLU ± S.E.M. (n=5) Asterisks indicate statistically significant different to control group (p<0.05).