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. 2020 Jun 10;45(13):2257–2266. doi: 10.1038/s41386-020-0732-x

Fig. 1. Effects of colon-delivered SCFAs on cortisol response to acute psychosocial stress.

Fig. 1

Responses to the Maastricht Acute Stress Test (MAST) at pre- and post-intervention. Cortisol responses to acute psychosocial stress induction procedure. Saliva samples were collected from 20 min before the stress induction, up to 65 min after stress induction. Both the low and high SCFA dose groups exhibited significantly greater decreases in cortisol response in comparison to the placebo group (p = 0.035). Graphs show means of Box-Cox transformed cortisol (transformed_cortisol = ((cortisol + 1)**−0.5 − 1)/−0.5) concentrations ± SE.