Fig. 4. Overview of the metabolic capabilities of non-gut-associated Elusimicrobia.
a Lineage IV and V. b Lineage IX. Abbreviations not defined in the text: GHS, glycoside hydrolases; TCA, tricarboxylic acid cycle; 2-oxo, 2-oxoglutarate; Suc-CoA, succinyl-CoA; DH, dehydrogenase; HYD, hydrogenase; PPi, pyrophosphate; Pi, inorganic phosphate; PRPP, Phosphoribosyl pyrophosphate; G3P, glyceraldehyde-3-phosphate; PEP, phosphoenolpyruvate; OAA, oxaloacetate; MEP pathway, 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate pathway; IPP, isopentenyl pyrophosphate; DMAPP, dimethylallylpyrophosphate; FeS, FeS oxidoreductase; ETF, electron transfer flavoprotein; ETF:QO, Electron-transferring flavoprotein dehydrogenase/ubiquinone oxidoreductase; BCD/ETFAB, butyryl-CoA dehydrogenase/electron-transfer flavoprotein complex; 3HB-CoA, 3-hydroxybutyryl-CoA dehydrogenase; 3-H-CoA, 3-hydroxyacyl-CoA; 3-keto-CoA, 3-ketoacyl-CoA; H+PPase, proton-translocating pyrophosphatase; Cx V, ATP synthase; Cx I, NADH dehydrogenase; Cx II, succinate dehydrogenase/fumarate reductase; Alt Cx III, alternative complex III; Cx IV, cytochrome c oxidase or cytochrome bd oxidase; NorBC, nitric-oxide reductase; NirS, cytochrome cd1-type nitrite reductase; cyt c, c-type cytochrome; NapA, periplasmic nitrate reductase; NxR, nitrite/nitrate oxidoreductase; NrfAH, nitrite reductase; Mrp, multi-subunit Na+/H+ antiporter; WL pathway, Wood–Ljungdahl pathway; THF, tetrahydrofolate; Rnf, Ferredoxin:NAD+-Oxidoreductase.