Table 1. Significant changes of PPPs expression in transcription level between pancreatic cancer and normal pancreas.
Genes | Isoforms | Pancreatic cancer versus pancreas | Fold change | P-value | t-test | Reference |
---|---|---|---|---|---|---|
PPP1C | PPP1CA | Pancreatic adenocarcinoma versus Normal | 1.786 | 2.47E-05 | 5.633 | Iacobuzio [27] |
Pancreatic adenocarcinoma versus Normal | 1.847 | 6.39E-05 | 4.636 | Pei [24] | ||
PPP1CB | Pancreatic adenocarcinoma versus Normal | 1.985 | 0.001 | 3.724 | Segara [25] | |
PPP1CC | NA | NA | NA | NA | NA | |
PPP2C | PPP2CA | NA | NA | NA | NA | NA |
PPP2CB | NA | NA | NA | NA | NA | |
PPP3C | PPP3CA | Pancreatic adenocarcinoma versus Normal | 2.564 | 6.95E-04 | 3.911 | Segara [25] |
Pancreatic adenocarcinoma versus Normal | 2.077 | 1.74E-09 | 7.233 | Badea [26] | ||
PPP3CB | Pancreatic adenocarcinoma versus Normal | 3.267 | 0.001 | 4.739 | Logsdon [23] | |
PPP3CC | NA | NA | NA | NA | NA | |
PPP4C | Pancreatic adenocarcinoma versus Normal | 1.871 | 6.76E-05 | 5.417 | Logsdon [23] | |
Pancreatic adenocarcinoma versus Normal | 6.153 | 0.005 | 2.877 | Grutzmann [22] | ||
Pancreatic carcinoma versus Normal | 1.730 | 7.26E-07 | 6.048 | Pei [24] | ||
PPP5C | NA | NA | NA | NA | NA | |
PPP6C | NA | NA | NA | NA | NA | |
PPP7C | PPEF1 | Pancreatic carcinoma versus Normal | 1.642 | 2.50E-05 | 4.439 | Pei [24] |
PPEF2 | NA | NA | NA | NA | NA |
Abbreviation: NA, no association.