Table 4. Univariate and multivariate survival analysis of clinicopathological variables in patients with pancreatic cancer.
| Factors | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P-value | HR | 95%CI | P-value | |
| Age | ||||||
| ≥60 | Ref | |||||
| <60 | 1.292 | 0.689–2.422 | 0.425 | |||
| Sex | ||||||
| Male | Ref | |||||
| Female | 0.549 | 0.269–1.123 | 0.101 | |||
| Primary tumor location | ||||||
| Head and neck | Ref | |||||
| Body and tail | 0.971 | 0.521–1.810 | 0.926 | |||
| Nuclear grade | ||||||
| I-II | Ref | Ref | ||||
| III | 2.421 | 1.146–5.117 | 0.021 | 2.399 | 1.077–5.347 | 0.032 |
| Vascular invasion | ||||||
| No | Ref | |||||
| Yes | 1.578 | 0.848–2.939 | 0.150 | |||
| T stage | ||||||
| 1-2 | Ref | |||||
| 3 | 0.704 | 0.276–1.798 | 0.464 | |||
| N stage | ||||||
| 0 | Ref | Ref | ||||
| 1 | 3.453 | 1.803–6.611 | <0.001 | 2.583 | 1.269–5.257 | 0.009 |
| Jaundice | ||||||
| No | Ref | |||||
| Yes | 1.135 | 0.556–2.316 | 0.728 | |||
| Abdominal pain | ||||||
| No | Ref | |||||
| Yes | 0.765 | 0.412–1.421 | 0.396 | |||
| PPP3CB | ||||||
| Low expression | Ref | Ref | ||||
| High expression | 0.114 | 0.052–0.248 | <0.001 | 0.164 | 0.075–0.360 | <0.001 |