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. Author manuscript; available in PMC: 2021 Jan 5.
Published in final edited form as: J Biomed Mater Res B Appl Biomater. 2020 May 9;108(7):2981–2994. doi: 10.1002/jbm.b.34628

TABLE 4.

Optimized batch selected based on constraints applied

Variables Goal Lower limit Upper limit Predicted optimized batch parameters
Optimization of bio-inks
 A: Gelatin concentration (%) Maximize 2.00 4.00 4.00
 B: Alginate concentration (%) 3.25 2.00 4.00 3.25
 Temperature (°C) Minimize 23 27 23