Table 2.
The most common ATC classes over the course of ESRD: before kidney transplantation, on discharge after kidney transplantation (M0), and 4 and 12 months after kidney transplantation (M4 and M12)
| ATC classes prescribed to patients | ||||
|---|---|---|---|---|
| ATC classes | Before |
M0 |
M4 |
M12 |
| n (%) | n (%) | n (%) | n (%) | |
| Cardiovascular system | 901 (33) | 767 (21) | 896 (24) | 1000 (29) |
| Beta blocking agents | 185 | 195 | 221 | 231 |
| Calcium channel blockers | 113 | 222 | 207 | 199 |
| Central antihypertensives | 78 | 180 | 161 | 172 |
| Lipid-modifying agents | 173 | 48 | 130 | 176 |
| Agents acting on the renin-angiotensin system | 171 | 33 | 85 | 128 |
| Diuretics | 163 | 77 | 78 | 79 |
| Cardiac therapy | 17 | 9 | 12 | 13 |
| Vasoprotectives | 0 | 3 | 2 | 2 |
| Peripheral vasodilators | 1 | 0 | 0 | 0 |
| Alimentary tract and metabolism | 536 (20) | 615 (17) | 751 (20) | 792 (23) |
| Drugs for acid-related disorders | 142 | 323 | 277 | 242 |
| Vitamins | 201 | 37 | 192 | 267 |
| Drugs used in diabetes | 66 | 109 | 152 | 159 |
| Mineral supplements | 98 | 95 | 102 | 94 |
| Antidiarrheals, intestinal anti-inflammatory/anti-infective agents | 9 | 19 | 12 | 13 |
| Drugs for constipation | 7 | 19 | 6 | 9 |
| Drugs for functional gastrointestinal disorders | 6 | 10 | 3 | 3 |
| Digestives, including enzymes | 3 | 2 | 3 | 3 |
| Bile and liver therapy | 2 | 0 | 1 | 2 |
| Stomatological preparations | 0 | 1 | 3 | 0 |
| Other alimentary tract and metabolism products | 2 | 0 | 0 | 0 |
| Antineoplastic and immunomodulating agents | 13 (0.5) | 703 (19) | 678 (18) | 651 (19) |
| Immunosuppressants | 13 | 703 | 678 | 651 |
| Blood and blood-forming organs | 366 (14) | 407 (11) | 386 (10) | 332 (10) |
| Antianemic preparations | 255 | 255 | 220 | 160 |
| Antithrombotic agents | 110 | 149 | 165 | 172 |
| Blood substitutes and perfusion solutions | 0 | 3 | 1 | 0 |
| Antihemorrhagics | 1 | 0 | 0 | 0 |
| Systemic hormonal preparations, excluding sex hormones and insulins | 155 (6) | 314 (9) | 338 (9) | 353 (10) |
| Corticosteroids for systemic use | 42 | 288 | 289 | 300 |
| Calcium homeostasis | 93 | 6 | 32 | 35 |
| Thyroid therapy | 20 | 19 | 17 | 18 |
| Pancreatic hormones | 0 | 1 | 0 | 0 |
| Anti-infectives for systemic use | 7 (0.3) | 469 (13) | 328 (9) | 56 (2) |
| Antibacterials for systemic use | 1 | 319 | 214 | 23 |
| Antivirals for systemic use | 4 | 136 | 103 | 30 |
| Antimycotics for systemic use | 0 | 13 | 8 | 2 |
| Immune sera and immunoglobulins | 1 | 0 | 3 | 1 |
| Antimycobacterials | 1 | 1 | 0 | 0 |
| Nervous system | 157 (6) | 160 (4) | 113 (3) | 122 (4) |
| Psycholeptics | 86 | 92 | 60 | 56 |
| Analgesics | 23 | 35 | 20 | 25 |
| Antiepileptics | 24 | 15 | 15 | 25 |
| Psychoanaleptics | 21 | 13 | 11 | 14 |
| Other nervous system drugs | 2 | 5 | 3 | 2 |
| Anti-Parkinson drugs | 1 | 0 | 0 | 0 |
| Various | 427 (16) | 22 (1) | 32 (1) | 17 (0.5) |
| Drugs for treatment of hyperkalemia and hyperphosphatemia | 420 | 19 | 32 | 16 |
| Detoxifying agents for antineoplastic treatment | 7 | 3 | 0 | 1 |
| Other pharmacological classes | 145 (5) | 165 (5) | 179 (5) | 121 (4) |
| Antiparasitic products, insecticides and repellents | 0 | 101 | 85 | 8 |
| Musculoskeletal system | 48 | 2 | 20 | 42 |
| Sodium bicarbonate | 19 | 23 | 37 | 30 |
| Genito urinary system and sex hormones | 21 | 11 | 23 | 22 |
| Respiratory system | 37 | 12 | 12 | 10 |
| Sensory organs | 4 | 14 | 1 | 5 |
| Dermatologicals | 2 | 2 | 1 | 4 |
| No ATC code | 12 | 0 | 0 | 0 |
| Not marketed in France | 2 | 0 | 0 | 0 |
| Total | 2707 | 3622 | 3701 | 3444 |
ATC, anatomical, therapeutic, and chemical; ESRD, end-stage renal disease.
The main drug classes appear in bold. The denominator is the total number of drug prescriptions.