Table 3.
Fractional Inhibitory Concentration Index (FICI) for the combination of ZnO NPs with Meropenem, Ciprofloxacin, and Colistin.
Organism | FICI values |
||
---|---|---|---|
Meropenem | Ciprofloxacin | Colistin | |
P. aeruginosa ATCC 27853 | 1.1 (I) ± 0.2 | N/T | 0.41 (S) ± 0.09 |
P. aeruginosa MRO-17-29 | 1.8 (I) ± 0.2 | N/T | N/T |
P. aeruginosa MRO-17-3 | N/T | 0.76 (A) ± 0.2 | N/T |
P. aeruginosa MRO-16-3 | N/T | N/T | 0.24 (S) ± 0.04 |
P. aeruginosa MRO-16-4 | N/T | N/T | 0.39 (S) ± 0.1 |
P. aeruginosa MRO-16-1 | N/T | N/T | 0.64 (A) ± 0.4 |
P. aeruginosa MRO-16-7 | N/T | N/T | 0.55 (A) ± 0.01 |
(S) Synergy, (A) Additive, (I) Indifference, (N/T) not been tested.
*FICI value interpretation: Synergy ≤ 0.5, additive > 0.5 and ≤ 1.0, Indifference > 1 and ≤ 4.0 and Antagonism > 4.0.