Table 2:
Dosimetric variables and their univariate correlation (HR [95% confidence interval (CI)] and p-value) with RP2+
| Variable (Units) | Median value (range) |
HR (per Gy or per %) [95% CI] | p-value |
|---|---|---|---|
| Ipsilateral-lung mean dose (Gy) | 21.3 (3.0-45.2) | 1.070 [1.014-1.113] | 0.012 |
| Ipsilateral-lung min dose (Gy) | 0.6 (<0.01-5.3) | 1.438 [0.964-2.145] | 0.07 |
| Contralateral-lung mean dose (Gy) | 6.1 (0.4-19.8) | 1.007 [0.992-1.021] | 0.33 |
| Contralateral-lung min dose (Gy) | 0.46 (<0.01-0.46) | 1.009 [0.974-1.045] | 0.61 |
| Right lung mean dose (Gy) | 17.3 (2.3-33.5) | 1.006 [0.964 - 1.050] | 0.77 |
| Right lung min dose (Gy) | 0.49 (<0.01-3.85) | 1.597 [0.921-2.768] | 0.089 |
| Left lung mean dose (Gy) | 6.78 (0.36-45.2) | 1.0340 [1.000-1.069] | 0.0460 |
| Left lung min dose (Gy) | 0.37 (<0.01-5.27) | 1.502 [1.021-1.210] | 0.0350 |
| Lungs mean dose (Gy) | 11.9 (1.8-19.5) | 1.189 [1.064-1.328] | 0.0018 |
| Lungs min dose (Gy) | 0.30 (< 0.01 - 1.39) | 5.366 [1.889-15.241] | 0.0012 |
| Lungs V20 (%) | 21.3 (1.7-44.8) | 1.090 [1.035- 1.148] | 0.0008 |
| Heart mean dose (Gy) | 11.2 (9.4-33.4) | 1.0656 [1.0213-1.1117] | 0.0027 |
| Heart min dose (Gy) | 0.55 (<0.01-8.11) | 1.284 [1.055-1.563] | 0.0110 |
| Lung D75 (Gy) | 1.85 (0.25-8.25) | 1.369 [1.148-1.633] | 0.0004 |
| Lung V4 (%) | 54.3 (5.4-92.1) | 1.040 [1.018-1.063] | 0.0003 |
| Lung V5 (%) | 50.2 (4.7-88) | 1.039 [1.016-1.062] | 0.0005 |
| Heart D60 (Gy) | 2.35 (0.15-41.1) | 1.068 [1.026-1.110] | 0.0009 |
| Heart V16 (%) | 23.0 (<0.1-90.5) | 1.025 [1.009-1.040] | 0.0011 |