. Author manuscript; available in PMC: 2022 Jan 1.

Published in final edited form as: Pract Radiat Oncol. 2020 Oct 14;11(1):e52–e62. doi: 10.1016/j.prro.2020.09.014

Table 2:

Dosimetric variables and their univariate correlation (HR [95% confidence interval (CI)] and p-value) with RP2+

Variable (Units)	Median value (range)	HR (per Gy or per %) [95% CI]	p-value
Ipsilateral-lung mean dose (Gy)	21.3 (3.0-45.2)	1.070 [1.014-1.113]	0.012
Ipsilateral-lung min dose (Gy)	0.6 (<0.01-5.3)	1.438 [0.964-2.145]	0.07
Contralateral-lung mean dose (Gy)	6.1 (0.4-19.8)	1.007 [0.992-1.021]	0.33
Contralateral-lung min dose (Gy)	0.46 (<0.01-0.46)	1.009 [0.974-1.045]	0.61
Right lung mean dose (Gy)	17.3 (2.3-33.5)	1.006 [0.964 - 1.050]	0.77
Right lung min dose (Gy)	0.49 (<0.01-3.85)	1.597 [0.921-2.768]	0.089
Left lung mean dose (Gy)	6.78 (0.36-45.2)	1.0340 [1.000-1.069]	0.0460
Left lung min dose (Gy)	0.37 (<0.01-5.27)	1.502 [1.021-1.210]	0.0350
Lungs mean dose (Gy)	11.9 (1.8-19.5)	1.189 [1.064-1.328]	0.0018
Lungs min dose (Gy)	0.30 (< 0.01 - 1.39)	5.366 [1.889-15.241]	0.0012
Lungs V20 (%)	21.3 (1.7-44.8)	1.090 [1.035- 1.148]	0.0008
Heart mean dose (Gy)	11.2 (9.4-33.4)	1.0656 [1.0213-1.1117]	0.0027
Heart min dose (Gy)	0.55 (<0.01-8.11)	1.284 [1.055-1.563]	0.0110

Lung D₇₅ (Gy)	1.85 (0.25-8.25)	1.369 [1.148-1.633]	0.0004
Lung V₄ (%)	54.3 (5.4-92.1)	1.040 [1.018-1.063]	0.0003
Lung V₅ (%)	50.2 (4.7-88)	1.039 [1.016-1.062]	0.0005
Heart D₆₀ (Gy)	2.35 (0.15-41.1)	1.068 [1.026-1.110]	0.0009
Heart V₁₆ (%)	23.0 (<0.1-90.5)	1.025 [1.009-1.040]	0.0011