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Local type 2 cytokine production in K5 Nrf2−/− and Nrf2 flox/flox mice induced by papain exposure. Concentrations of IL-5, and IL-13 in sinonasal tissue homogenates. Data represented mean±SEM. *p<0.05. In brief, there is a higher level of IL-13 overexpression in the K5 Nrf2−/− mouse. IL-5 levels did not change with epithelial specific knockout of Nrf2.
