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. Author manuscript; available in PMC: 2021 Jan 6.
Published in final edited form as: Clin Cancer Res. 2020 Nov 2;27(1):158–168. doi: 10.1158/1078-0432.CCR-20-3184

Figure 2 |. Enrichment of JMML driver mutations in DNA methylation subgroups.

Figure 2 |

(A-C) Confusion table comparing the published methylation subgroups to the meta-analysis consensus clustering. EWOG-MDS patients (A) and US patients (B) were classified in three methylation subgroups in the original publication whereas the Japanese study (C) separated patients in two methylation subgroups. (D) Absolute and relative numbers of patients with a specific JMML driver mutation and their distribution across the DNA methylation subgroups are depicted. Odd ratios, confidence intervals and p-values were calculated using Fisher’s exact test.