Table 1. Patient Demographics.
Discovery Set 1 | % | Discovery Set 2 | % | Blinded Multi-Institution Validation Cohort |
% | |
---|---|---|---|---|---|---|
Total | 35 | 48 | 74 | |||
Disease Group Age median, IQR | 50 (43-64) | 59.5 (50-68.5) | 56 (46-66.5) | |||
Healthy Group Age median, IQR | 31.5 (26-52.75) | 26.5 (24-29.75) | 55.5 (48.5-63.3) | |||
Non-Tumor Group Age median, IQR | N/A | N/A | 66 (62-67) | |||
Sex | ||||||
Male | 16 | 45.7 | 25 | 52.1 | 46 | 62.2 |
Female | 19 | 54.3 | 23 | 47.9 | 28 | 37.8 |
Race, n (%) | ||||||
White | 31 | 88.6 | 43 | 89.6 | 65 | 87.8 |
Asian | 1 | 2.9 | 2 | 4.2 | 3 | 4.1 |
Black | 0 | 0.0 | 0 | 0.0 | 3 | 4.1 |
Other | 2 | 5.7 | 1 | 2.1 | 0 | 0.0 |
Unavailable | 1 | 2.9 | 2 | 4.2 | 3 | 4.1 |
Ethnicity, n (%) | ||||||
Hispanic | 1 | 2.9 | 2 | 4.2 | 0 | 0.0 |
Non-Hispanic | 30 | 85.7 | 40 | 83.3 | 55 | 74.3 |
Unavailable | 4 | 11.4 | 6 | 12.5 | 19 | 25.7 |
WHO Grade, n (%) | ||||||
II | 3 | 8.6 | 2 | 4.2 | 2 | 2.7 |
III | 3 | 8.6 | 4 | 8.3 | 10 | 13.5 |
IV | 16 | 45.7 | 32 | 66.7 | 33 | 44.6 |
N/A | 13 | 37.1 | 10 | 20.8 | 29 | 39.2 |
Disease Status | ||||||
Newly Diagnosed | 21 | 60.0 | 30 | 62.5 | 39 | 52.7 |
Recurrent | 4 | 11.4 | 8 | 16.7 | 18 | 24.3 |
N/A | 17 | 23.0 | ||||
Medications, n (%) | ||||||
anticonvulsants (levetriacetam, clonazepam, lacosomide, carbamazepine, lamotrigine) | 16 | 45.7 | 13 | 27.1 | 30 | 40.5 |
steroids (dexamethasone) | 7 | 20.0 | 10 | 20.8 | 18 | 24.3 |
blood thinner (aspirin, coumadin) | 3 | 8.6 | 4 | 8.3 | 9 | 12.2 |
prior radiation therapy | 1 | 2.9 | 5 | 10.4 | 2 | 2.7 |
prior chemotherapy | 2 | 5.7 | 8 | 16.7 | 4 | 5.4 |
clinical trial participant | 1 | 2.9 | 1 | 2.1 | 6 | 8.1 |