Table 1.
Descriptive statistics for clinical and imaging-derived measures of temperature, blood flow, average metabolite values (in institutional units), and metabolite ratios.
| time1 (N = 18) | time2 (N = 18) | time1 vs. time2 | |
|---|---|---|---|
| Heart rate (bpm) | 73.50 ± 11.40 | 74.17 ± 17.12 | t(17) = −0.20, p = 0.84 |
| HADS, depression | 1.72 ± 1.96 | 2.72 ± 2.27 | t(17)= −4.12, p = 0.001 |
| HADS, anxiety | 5.33 ± 2.63 | 4.83 ± 2.36 | t(17) = 0.89, p = 0.39 |
| POMS, TMD | −0.39 ± 20.75 | 0.06 ± 18.89 | t(17) = −0.18, p = 0.85 |
| Tympanic temperature (°C) | 36.73 ± 0.30 | 36.65 ± 0.19 | t(17) = 0.98, p = 0.34 |
| Global TCRE (°C) | 37.00 ± 0.62 | 37.40 ± 0.94 | t(17) = −1.28, p = 0.22 |
| Global CBF (ml/100 g/min) | 70.77 ± 6.15 | 71.03 ± 4.24 | t(17) = 0.21, p = 0.84 |
| tCre | 26270.0 ± 1807 | 26844.98 ± 1345.20 | t(17) = −1.91, p = 0.07 |
| tCho | 5279.00 ± 664.10 | 5288.66 ± 723.35 | t(17) = −0.10, p = 0.93 |
| NAA/tCre | 1.35 ± 0.24 | 1.26 ± 0.09 | t(17) = 2.19, p = 0.04 |
| Glx/tCre | 0.66 ± 0.06 | 0.64 ± 0.05 | t(17) = 1.76, p = 0.10 |
| MI/tCre | 0.55 ± 0.08 | 0.59 ± 0.22 | t(17) = −0.63, p = 0.53 |
*All measures are in I.U., institutional units unless otherwise specified.
HADS, Hospital Anxiety and Depression Scale; POMS, Profile of Mood States; TMD, total mood disturbance; CBF, cerebral blood flow; tCho, total choline; tCre, creatine + phosphocreatine (total creatine); NAA/tCre, N-acetylaspartate ratio to tCre; Glx/tCr, ratio of combined signal from glutamine and glutamate to tCre; MI/tCre, myo-inositol ratio to tCre; I.U., institutional units.