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. 2021 Jan 5;7:1. doi: 10.1038/s41522-020-00173-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Observed richness and Simpsons 1-D (a measure of diversity) are shown in panels a and b respectively. Only a significant difference (**) was observed for nasal samples for those aged 5–17 when compared against 50–65 (p = 0.0023). Beta diversity is shown using Double Principle Co-ordinates Analysis (DPCoA) (panel c). Here, clusters are observed for nasal samples (left) with grouping based on age group. No clusters were observed for oral samples (right).