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. 2020 Dec 23;11:608696. doi: 10.3389/fimmu.2020.608696

Figure 3.

Figure 3

Daily measurements of CD64, CCR2, and CXCR2 surface level; apoptosis; and NETosis stratified by Day 14 clinical status (Recovered, Critically-ill, or Deceased). MFI of CD64, CCR2, and CXCR2 surface receptors; the percentages of “dysfunction neutrophils” (i.e., CD64-positive neutrophils, CCR2-positive neutrophils, and CXCR2-negative neutrophils); the percentages of apoptosis; and the percentages of NETosis were illustrated in line graphs with error bars grouped by Day 14 clinical status. The lines connected median value of the measurements on the specific days. Error bars delineated interquartile ranges. Depending on data distribution, either one-way ANOVA test or Kruskal Wallis test with Dunn’s test of multiple comparison was employed to compare the measurements of each neutrophil function on specific days between groups. *p-value from ANOVA or Kruskal Wallis tests < 0.05. ANOVA, analysis of variance; CCR2, C-C chemokine receptor 2; CD64, cluster of differentiation 64; CXCR2, C-X-C chemokine receptor 2, MFI, median fluorescent intensity.