Table 3.
Correlation between HHEX expression and clinicopathological features.
OS | RFS | |||
---|---|---|---|---|
Characteristic | HR (95% CI) | Log rank P | HR (95% CI) | Log rank P |
GENE SYMBOL: HHEX, affy id:215933_s_at | ||||
ER status | ||||
ER positive | 0.88(0.62–1.26) | 0.4927 | 0.82(0.7–0.97) | 0.0191 |
ER negative | 0.78(0.49–1.23) | 0.2826 | 0.82(0.65–1.02) | 0.0792 |
HER2 status | ||||
HER2 positive | 1.52(0.74–3.12) | 0.2518 | 0.83(0.54–1.28) | 0.3982 |
HER2 negative | 1.06(0.45–2.51) | 0.8886 | 0.68(0.52–0.88) | 0.0038 |
Lymph node status | ||||
Lymph node positive | 0.65(0.44–0.96) | 0.0278 | 0.63(0.52–0.77) | 4.00E-06 |
Lymph node negative | 0.92(0.63–1.33) | 0.6414 | 0.75(0.63–0.89) | 0.0009 |
Grade | ||||
1 | 1.25(0.52–3.02) | 0.6169 | 0.86(0.51–1.45) | 0.5758 |
2 | 0.78(0.5–1.2) | 0.2502 | 0.73(0.57–0.93) | 0.0094 |
3 | 0.85(0.61–1.18) | 0.3365 | 0.9(0.72–1.12) | 0.3396 |
Intrinsic subtype | ||||
Basal | 0.8(0.49–1.3) | 0.3599 | 0.64(0.5–0.83) | 0.0006 |
luminal A | 0.72(0.5–1.02) | 0.066 | 0.74(0.62–0.88) | 0.0006 |
luminal B | 0.94(0.65–1.36) | 0.7459 | 0.69(0.57–0.84) | 2.00E-04 |
HER2+ | 0.29(0.14–0.6) | 0.0004 | 0.56(0.38–0.83) | 0.0033 |
The bold fonts means the values with statistical significance.