Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 23;7:608368. doi: 10.3389/fmolb.2020.608368

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Cao, Zhang, Xu, Lin, Chang, Wang, Huang, Chen, Wang and Song.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A): Consensus map of NMF clustering. (B) Cophenetic, rss, and dispersion distributions with ranks from 2 to 10. Cophenetic correlation is obtained based on the concordance matrix proposed by Brunet et al. and it is used to reflect the stability of the clusters obtained from NMF. The value of cophenetic correlation is between 0 and 1, and the larger the value, the more stable the clusters. The rss refers to the residual sum of squares, which is used to reflect the clustering performance of the model. The smaller the value, the better the clustering performance of the model. Theoretically, this value is the smallest when each sample is clustered into 1 class, but such results are not available in practice, so it needs to be used in combination with other indicators. (C) Heat map of the expression of the prognosis-related genes in the different subtypes.