Table 1.
Demographic and selected clinical features of AOSD patients.
| Variables | All patients | Patients with liver involvement | Patients without liver involvement | p-values |
|---|---|---|---|---|
| n = 128 | n = 104 | n = 24 | ||
| Age (years) | 35 (27, 47) | 35 (27, 47) | 35 (28, 49) | 0.903 |
| Female | 102 (79.7) | 79 (76) | 23 (95.8) | 0.027 |
| Body mass index (kg/m2) | 21.47 (19.48, 23.31) | 21.47 (19.40, 23.04) | 21.59 (19.66, 23.57) | 0.696 |
| Diabetes mellitus | 9 (7) | 8 (7.7) | 1 (4.2) | 1.000 |
| Hypertension | 8 (6.3) | 6 (5.8) | 2 (8.3) | 0.643 |
| Disease duration (month) | 2.3 (1.03, 10.04) | 1.88 (0.92, 8.17) | 4.46 (1.43, 18.37) | 0.035 |
| Fever > 39°C | 121 (94.5) | 98 (94.2) | 23 (95.8) | 1.000 |
| Typical skin rash | 57 (44.5) | 44 (42.3) | 13 (54.2) | 0.292 |
| Pleuritis | 60 (46.9) | 54 (51.9) | 6 (25) | 0.017 |
| Pneumonia | 44 (34.4) | 41 (39.4) | 3 (12.5) | 0.016 |
| Pericarditis | 30 (23.4) | 30 (28.8) | 0 (0) | 0.001 |
| Myalgia | 65 (50.8) | 54 (51.9) | 11 (45.8) | 0.591 |
| Splenomegaly | 68 (53.1) | 59 (56.7) | 9 (37.5) | 0.089 |
| Hepatomegaly | 18 (14.1) | 18 (17.3) | 0 (0) | 0.024 |
| Lymphadenopathy | 115 (89.8) | 92 (88.5) | 23 (95.8) | 0.460 |
| Sore throat | 103 (80.5) | 82 (78.8) | 21 (87.5) | 0.406 |
| Abdominal pain | 12 (9.4) | 11 (10.6) | 1 (4.2) | 0.462 |
| Arthralgia | 120 (93.8) | 96 (92.3) | 24 (100) | 0.350 |
| Arthritis | 56 (43.8) | 45 (43.3) | 11 (45.8) | 0.819 |
| Leukocytes > 15,000/mm3 | 79 (61.7) | 63 (60.6) | 16 (66.7) | 0.580 |
| Ferritin > 5 ULN | 99 (77.3) | 85 (81.7) | 14 (58.3) | 0.014 |
| Systemic score | 7 (5, 8) | 7 (6, 8) | 5 (4.25, 6) | <0.001 |
Data are presented as median (IQR) for continuous variables, and as frequency counts (%) for categorical variables. ULN, upper limit of normal. A p < 0.05 is shown in bold type.