Table 2.
Vascular-system-related parameters among clinical data of critically ill patients with COVID-19a
| Without HT | S1 HT | S2 HT | S3 HT | |
|---|---|---|---|---|
| No. of patients (%) | 48 (39.0) | 29 (23.6) | 24 (20.0) | 22 (17.9) |
| RAAS inhibitors (%) | 0 | 2 (6.8) | 2 (8.3) | 4 (18.2) |
| Comorbidities, no. (%) | ||||
| Diabetes | 8 (16.3) | 6 (20.7) | 4 (16.7) | 11 (50.0)** |
| Coronary heart disease | 5 (10.2) | 7 (24.1) | 2 (8.3) | 7 (31.8)* |
| Cerebrovascular disease | 5 (10.2) | 5 (17.2) | 7 (29.2) | 5 (22.7) |
| Chronic kidney disease | 4 (8.2) | 5 (17.2) | 2 (8.3) | 5 (22.7) |
| COPD | 2 (4.1) | 3 (10.3) | 3 (12.5) | 2 (9.1) |
| Laboratory tests on admission, median (IQR) | ||||
| CRP, mg/L | 48.2 (11.1–105.4) | 27.2 (8.9–95.7) | 80.0 (8.7–128.3) | 92.8 (32.2–136.6)* |
| Procalcitonin, ng/mL | 0.21 (0.07–0.57) | 0.20 (0.08–0.30) | 0.27 (0.10–0.50) | 0.86 (0.12–2.60)* |
| Myoglobin, ng/mL | 29.7 (7.1–126.5) | 32.7 (20.3–381.0) | 113.9 (8.2–485.3)* | 103.2 (19.6–406.6)* |
| High-sensitivity troponin I, ng/mL | 0.02 (0.01–0.07) | 0.01 (0.02–0.20) | 0.01 (0.01–0.20) | 0.04 (0.03–0.89)* |
| Creatine kinase, IU/L | 52.7 (31.9–108.3) | 33.2 (20.7–75.0) | 48.3 (37.4–111.4) | 95.2 (33.6–713.5)* |
| BNP, pg/mL | 104.3 (46.5–186.6) | 395.0 (47.0–524.7) | 46.6 (0.01–60.0) | 285.6 (53.9–1401.0)* |
| Creatinine, μmol/L | 58.6 (48.8–76.0) | 68.7 (43.7–90.0)* | 73.1 (62.5–146.0)* | 104.0 (56.8–185.0)* |
| Complications [No. of patients (%)] | ||||
| ARDS | 20 (41.7) | 14 (48.3) | 14 (58.3) | 15 (68.2) |
| Cardiac injury | 13 (27.1) | 13 (44.8) | 15 (62.5)* | 20 (90.9)** |
| Kidney injury | 8 (16.7) | 7 (24.1) | 4 (16.7) | 9 (40.9)* |
| Died | 22 (44.9) | 13 (44.8) | 8 (33.3) | 14 (63.6) |
COPD chronic obstructive pulmonary disease, CRP C-reactive protein, BNP type B natriuretic peptide, ARDS acute respiratory distress syndrome
aCategorical variables are presented as numbers and percentages. Continuous variables are shown as the median and interquartile range (IQR). Proportions for categorical variables were compared using the χ2 test. Fisher’s exact test was used if the sample size was small. Continuous variables were compared using independent group t-tests when the data were normally distributed, otherwise the Mann–Whitney test was used. *P < 0.05; **P < 0.001 vs. group without HT